Dietary supplementation with white button mushroom augments the protective immune response to Salmonella vaccine in mice

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Dietary supplementation with white button mushrooms augments the protective immune response to Salmonella vaccine in mice.

We previously showed that dietary white button mushrooms (WBMs) enhanced natural killer cell activity and that in vitro WBM supplementation promotes maturation and function of dendritic cells (DCs). The current study investigated whether WBM consumption would enhance pathogen-specific immune response using a Salmonella vaccination and infection animal model. C57BL/6 mice were fed diets containi...

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Dietary supplementation with white button mushroom enhances natural killer cell activity in C57BL/6 mice.

Mushrooms are reported to possess antitumor, antiviral, and antibacterial properties. These effects of mushrooms are suggested to be due to their ability to modulate immune cell functions. However, a majority of these studies evaluated the effect of administering extracts of exotic mushrooms through parental routes, whereas little is known about the immunological effect of a dietary intake of w...

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Previously, we showed that mice fed white button mushrooms (WBM) had enhanced immune functions known to help the body's antiviral defence. In the present study, we tested whether WBM conferred protection against viral infection. Young (4-month-old) and old (22-month-old) C57BL/6 mice were fed a diet containing 0, 2 or 10 % WBM powder for 8 weeks. Mice were then infected with influenza Puerto Ri...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2013

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.27.1_supplement.123.2